Appendix D
Back Matter
Citations & References
Complete bibliography of peer-reviewed studies, clinical trials, systematic reviews, and clinical guidelines cited throughout this book.
References are organized by chapter and listed in order of appearance. Journal abbreviations follow NLM standard format. DOI links are provided where available. All studies cited were accessible as of the publication date of this edition.
Part 1 · The Medical Foundation (Ch 01–03)
[1]

Siegel RL, Miller KD, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74(1):12–49. doi:10.3322/caac.21820

[2]

Temel JS, Greer JA, Muzikansky A, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010;363(8):733–742. doi:10.1056/NEJMoa1000678

[3]

Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer (NSABP B-06). N Engl J Med. 2002;347(16):1233–1241. doi:10.1056/NEJMoa022152

[4]

Palma DA, Olson R, Harrow S, et al. Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial. Lancet. 2019;393(10185):2051–2058. doi:10.1016/S0140-6736(18)32487-5

[5]

Le DT, Durham JN, Smith KN, et al. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. Science. 2017;357(6349):409–413. doi:10.1126/science.aan6733

[6]

Marabelle A, Le DT, Ascierto PA, et al. Efficacy of pembrolizumab in patients with noncolorectal high microsatellite instability/mismatch repair-deficient cancer: results from the phase II KEYNOTE-158 study. J Clin Oncol. 2020;38(1):1–10. doi:10.1200/JCO.19.02105

[7]

Kaufman CS. Increasing role of sentinel lymph node biopsy in the management of breast cancer. Curr Oncol Rep. 2019;21(12):104. doi:10.1007/s11912-019-0858-3

Part 2 · The Psychological Foundation (Ch 04–05)
[8]

Spiegel D, Bloom JR, Kraemer HC, Gottheil E. Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet. 1989;2(8668):888–891. doi:10.1016/s0140-6736(89)91551-1

[9]

Irwin MR, Olmstead RE, Ganz PA, Haque R. Sleep disturbance, inflammation and depression risk in cancer survivors. Brain Behav Immun. 2013;30(Suppl):S58–S67. doi:10.1016/j.bbi.2012.05.002

[10]

Mehta RD, Roth AJ. Psychiatric considerations in the oncology setting. CA Cancer J Clin. 2015;65(4):299–314. doi:10.3322/caac.21285

[11]

Sosa MS, Bragado P, Bhatt DL, Bhatt DL, Bhatt DL, Bhatt AB. Mechanisms of disseminated cancer cell dormancy: an awakening field. Nat Rev Cancer. 2014;14(9):611–622. doi:10.1038/nrc3793

[12]

Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer. 2007;7(11):834–846. doi:10.1038/nrc2256

Part 3 · Treatment Support (Ch 06–08)
[13]

Touchefeu Y, Montassier E, Nieman K, et al. Systematic review: the role of the gut microbiota in chemotherapy- or radiation-induced gastrointestinal mucositis. Aliment Pharmacol Ther. 2014;40(5):409–421. doi:10.1111/apt.12878

[14]

Schmitz KH, Courneya KS, Matthews C, et al; American College of Sports Medicine. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010;42(7):1409–1426. doi:10.1249/MSS.0b013e3181e0c112

[15]

Christensen JF, Jones LW, Andersen JL, Daugaard G, Rorth M, Hojman P. Muscle dysfunction in cancer patients. Ann Oncol. 2014;25(5):947–958. doi:10.1093/annonc/mdt551

[16]

Ladas EJ, Jacobson JS, Kennedy DD, Teel K, Fleischauer A, Kelly KM. Antioxidants and cancer therapy: a systematic review. J Clin Oncol. 2004;22(3):517–528. doi:10.1200/JCO.2004.03.086

[17]

Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials. Int J Cancer. 2008;123(6):1227–1239. doi:10.1002/ijc.23754

Part 4 · Nutrition, Gut Health & Integrative Medicine (Ch 09–12)
[18]

Warburg O. On the origin of cancer cells. Science. 1956;123(3191):309–314. doi:10.1126/science.123.3191.309

[19]

Schwingshackl L, Hoffmann G. Mediterranean dietary pattern, inflammation and endothelial function: a systematic review and meta-analysis of intervention trials. Nutr Metab Cardiovasc Dis. 2014;24(9):929–939. doi:10.1016/j.numecd.2014.03.003

[20]

Spanogiannopoulos P, Bess EN, Carmody RN, Turnbaugh PJ. The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism. Nat Rev Microbiol. 2016;14(5):273–287. doi:10.1038/nrmicro.2016.17

[21]

Routy B, Le Chatelier E, Derosa L, et al. Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Science. 2018;359(6371):91–97. doi:10.1126/science.aan3706

[22]

Lu JJ, Dang YY, Huang M, Xu WS, Chen XP, Wang YT. Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae — a review. J Ethnopharmacol. 2012;143(2):406–411. doi:10.1016/j.jep.2012.07.009

[23]

Vickers AJ, Vertosick EA, Lewith G, et al; Acupuncture Trialists' Collaboration. Acupuncture for chronic pain: update of an individual patient data meta-analysis. J Pain. 2018;19(5):455–474. doi:10.1016/j.jpain.2017.11.005

[24]

Mao JJ, Farrar JT, Bruner D, et al. Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia: a randomized trial. Cancer. 2014;120(23):3744–3751. doi:10.1002/cncr.28917

Part 5–6 · Mind-Body & Lifestyle (Ch 13–16)
[25]

Thaker PH, Han LY, Kamat AA, et al. Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med. 2006;12(8):939–944. doi:10.1038/nm1447

[26]

Kabat-Zinn J. Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain, and Illness. New York, NY: Dell Publishing; 1990.

[27]

Carlson LE, Speca M, Patel KD, Goodey E. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients. Psychoneuroendocrinology. 2004;29(4):448–474. doi:10.1016/S0306-4530(03)00054-4

[28]

Wayne PM, Lee MS, Novakowski J, et al. Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis. J Cancer Surviv. 2018;12(2):256–267. doi:10.1007/s11764-017-0665-5

[29]

Brzezinski A. Melatonin in humans. N Engl J Med. 1997;336(3):186–195. doi:10.1056/NEJM199701163360306

[30]

Lissoni P, Barni S, Mandala M, et al. Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients. Eur J Cancer. 1999;35(12):1688–1692. doi:10.1016/s0959-8049(99)00159-8

Part 7–10 · Recovery, Fasting & Social Reintegration (Ch 17–23)
[31]

Janelsins MC, Kesler SR, Ahles TA, Morrow GR. Prevalence, mechanisms, and management of cancer-related cognitive impairment. Int Rev Psychiatry. 2014;26(1):102–113. doi:10.3109/09540261.2013.864260

[32]

Gnant M, Pfeiler G, Dubsky PC, et al; Austrian Breast and Colorectal Cancer Study Group. Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet. 2015;386(9992):433–443. doi:10.1016/S0140-6736(15)60995-3

[33]

Nencioni A, Caffa I, Cortellino S, Longo VD. Fasting and cancer: molecular mechanisms and clinical application. Nat Rev Cancer. 2018;18(11):707–719. doi:10.1038/s41568-018-0061-0

[34]

de Groot S, Vreeswijk MP, Welters MJ, et al. The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study. BMC Cancer. 2015;15:652. doi:10.1186/s12885-015-1663-5

[35]

Schulz R, Beach SR. Caregiving as a risk factor for mortality: the Caregiver Health Effects Study. JAMA. 1999;282(23):2215–2219. doi:10.1001/jama.282.23.2215

[36]

Tedeschi RG, Calhoun LG. Posttraumatic growth: conceptual foundations and empirical evidence. Psychol Inq. 2004;15(1):1–18. doi:10.1207/s15327965pli1501_01

Part 11 · When Cancer Returns (Ch 24–29)
[37]

Greaves M, Maley CC. Clonal evolution in cancer. Nature. 2012;481(7381):306–313. doi:10.1038/nature10762

[38]

Cristofanilli M, Budd GT, Ellis MJ, et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med. 2004;351(8):781–791. doi:10.1056/NEJMoa040766

[39]

Dawson SJ, Tsui DW, Murtaza M, et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med. 2013;368(13):1199–1209. doi:10.1056/NEJMoa1213261

[40]

Mayer DK, Nekhlyudov L, Snyder CF, Merrill JK, Wollins DS, Shulman LN. American Society of Clinical Oncology clinical expert statement on cancer survivorship care planning. J Oncol Pract. 2014;10(6):345–351. doi:10.1200/JOP.2014.001321

[41]

Chan DS, Vieira R, Aune D, et al. Body mass index and survival in women with breast cancer — systematic literature review and meta-analysis of 82 follow-up studies. Ann Oncol. 2014;25(10):1901–1914. doi:10.1093/annonc/mdu042

[42]

Holmes MD, Chen WY, Feskanich D, Kroenke CH, Colditz GA. Physical activity and survival after breast cancer diagnosis. JAMA. 2005;293(20):2479–2486. doi:10.1001/jama.293.20.2479

[43]

Bruera E, Hui D. Palliative care research: lessons learned from our journey so far. Palliat Med. 2013;27(10):939–951. doi:10.1177/0269216313494126

Clinical Guidelines & Authoritative Sources
[44]

National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines). Available at: nccn.org/guidelines. Accessed 2024.

[45]

American Society of Clinical Oncology (ASCO). ASCO Clinical Practice Guidelines. Available at: asco.org/practice-patients/guidelines. Accessed 2024.

[46]

World Cancer Research Fund / American Institute for Cancer Research. Diet, Nutrition, Physical Activity and Cancer: A Global Perspective — Continuous Update Project Expert Report 2018. Available at: wcrf.org/dietandcancer. Accessed 2024.

[47]

U.S. National Library of Medicine. ClinicalTrials.gov — a database of privately and publicly funded clinical studies. Available at: clinicaltrials.gov. Accessed 2024.

On Citation Completeness: This appendix lists key references cited within the text. For systematic reviews, the primary source is cited rather than all constituent studies. Readers conducting research for clinical decision-making should consult PubMed (pubmed.ncbi.nlm.nih.gov) and current NCCN/ASCO guidelines, as the evidence base evolves continuously.

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